The rationale for people with Depression increasing glutathione is based on the evidence contained in the abstracts below, which describe the role of oxidative stress & abnormal glutathione levels in this disorder. This may be a contributory factor.
N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial.
Antioxidant enzyme activities and oxidative stress in affective disorders.
Antioxidative enzyme activities and lipid peroxidation in major depression: alterations by antidepressant treatments.
Antioxidative enzymes and increased oxidative stress in depressive women.
Antioxidant enzyme and malondialdehyde levels in patients with panic disorder.